past trainees

Recipient of an Individual NRSA Predoctoral Fellowship (2018 - 2020)
PhD Awarded 2020: "Post-lysosomal cholesterol trafficking"

Present Position: Postdoctoral Fellow, Carnegie Institution for Science
Department of Embryology

Publications:

Pugach EK, Feltes M, Kaufman RJ, Ory DS, Bang AG. High-content screen for modifiers of Niemann-Pick type C disease in patient cells. Hum Mol Genet. 2018 Jun 15;27(12):2101-2112.

Feltes M, Moores S, Gale SE, Krishnan K, Mydock-McGrane L, Covey DF, Ory DS, Schaffer JE. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. J Lipid Res. 2019 Mar;60(3):707-716.

Feltes M, Gale SE, Moores S, Ory DS, Schaffer JE. Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment. J Lipid Res. 2020 Mar;61(3):403-412.

Recipient of an Individual NRSA Predoctoral Fellowship (2020 - 2022)

Present Position: MD/PhD Candidate (anticipated May 2024)

Publications:

Hou P, Kang PW, Kongmeneck AD, Yang ND, Liu Y, Shi J, Xu X, White KM, Zaydman MA, Kasimova MA, Seebohm G, Zhong L, Zou X, Tarek M, Cui J. Two-stage electro-mechanical coupling of a K _V channel in voltage-dependent activation. Nat Commun. 2020 Feb 3;11(1):676.

Taylor KC, Kang PW, Hou P, Yang ND, Kuenze G, Smith JA, Shi J, Huang H, White KM, Peng D, George AL, Meiler J, McFeeters RL, Cui J, Sanders CR. Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife. 2020 Feb 25;9:e53901

Zhang G, Gibson RA, McDonald M, Liang P, Kang PW, Shi J, Yang H, Cui J, Mikati MA. A Gain-of-Function Mutation in KCNMA1 Causes Dystonia Spells Controlled With Stimulant Therapy. Mov Disord. 2020 Oct;35(10):1868-1873.

Present Position: PhD Candidate in Biomedical Engineering (anticipated 5/2021)

Publications:

Mangold KE, Brumback BD, Angsutararux P, Voelker TL, Zhu W, Kang PW, Moreno JD, Silva JR. Mechanisms and models of cardiac sodium channel inactivation. Channels (Austin). 2017 Nov 2;11(6):517-533.

Moreno JD, Zhu W, Mangold K, Chung W, Silva JR. A Molecularly Detailed Na _V 1.5 Model Reveals a New Class I Antiarrhythmic Target. JACC Basic Transl Sci. 2019 Oct 28;4(6):736-751.

 

 

Recipient of an Individual NRSA Predoctoral Fellowship (2019 - 2021)

Present Position: MD/PhD Candidate (anticipated May 2022)

Publications:

Li MW, Sletten AC, Lee J, Pyles KD, Matkovich SJ, Ory DS, Schaffer JE. Nuclear export factor 3 regulates localization of small nucleolar RNAs.  J Biol Chem. 2017 Dec 8;292(49):20228-20239.

Sletten AC, Peterson LR, Schaffer JE. Manifestations and mechanisms of myocardial lipotoxicity in obesity. J Intern Med. 2018 Nov;284(5):478-491.